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A December 2016 study of metabolites in ME/CFS (Chronic Fatigue Syndrome) patients found indicators showing impaired pyruvate dehydrogenase

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The blend wins on three axes: it consolidates one reconstitution event instead of three (which reduces the probability of an aseptic technique error somewhere in the chain), it locks the three peptides into one ratio so that a single 0.20 mL draw delivers a fixed combination, and it consumes one storage slot in the fridge instead of three

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Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, et al