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On the other hand, a high GSH content will help astrocytes to maintain their functions to protect the brain against oxidative stress and allows astrocytes to provide GSH precursors to neighboring neurons (Dringen et al

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SAR treatment significantly preserved the natural anxious behavior that was altered by soman exposure, likely through anti-inflammatory and antioxidant mechanisms that preserved limbic neurocircuitry, thereby promoting recovery in emotional behavior

Furthermore, enzymatic degradation of sulfated GAGs with heparinases and chondroitinase diminished HDL and LDL internalization and restored ferroptosis under lipoprotein-supplemented conditions