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The recent discovery of the role of small RNAs in governing the epigenetic status of individual genes offers exciting new possibilities in therapeutics and chemoprevention

As an advantage, BiTE can link T cells and tumor cells without restriction to MHC and induce T cells' activation, proliferation, and cytotoxic function efficiently [105]

Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion-induced ferroptosis via the keap1/Nrf2/GPX4 signaling pathway

An increased level of TNF- allows more ROS to generate in mitochondria, which significantly potentiates NF-B to exacerbate the cytokine storm, leading to cell death (9) (Figure 1)

Other adverse effects include nephrotoxicity and gastrointestinal symptoms, which usually resolve with dose reduction or discontinuation [114, 115]