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But the metabolic improvements these compounds produce may be even more significant for long-term health outcomes

What the transition requires, and what the evidence demands, is the same rigor applied to any therapeutic candidate: controlled trials, honest reporting of negative results, and clinical monitoring that matches the complexity of the interventions being deployed

doi: 10.1093/cid/ciaa1493 Saravolatz LD, Pawlak JM, Wegner C

For example, E2 increased human and murine Th1 differentiation by inducing T-bet and enhancing IFN production while also promoting IL-4 production and favoring Treg expansion (162169)

Chen CJ, Huang HS, Chang WC