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Lightens skin by reducing total melanin production and converting darker eumelanin into lighter pheomelanin

Higher doses of Isotretinoin can sometimes lead to more pronounced side effects

Risks and Side Effects While generally safe, potential issues include: Zinc Depletion: Long-term use may lower zinc levels, critical for growth and immunity

Author contributions NT performed most of the experiments in the cell lines, coordinated the collection of patient samples, processed all samples, conducted experiments, analyzed data, and wrote most of the manuscript

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