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The aconitate decarboxylase 1/Itaconate pathway modulates immune dysregulation and associates with cardiovascular disease markers and disease activity in systemic lupus erythematosus

Recent research has revealed that ferroptosis, through the release of lipid peroxidation products and DAMPs, can significantly affect the activity, phenotype, and function of tumor-infiltrating immune cells, thereby playing a dual role in tumor immune escape and immunotherapy response

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