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In the latter case, cell-free supernatants were immediately frozen in liquid nitrogen and stored at 80 C, while the corresponding cell pellets were either extracted for total RNA or lysed for protein analysis

A clinical study has confirmed elevated expression of NLRP3 inflammasome components in serum samples from pancreatitis patients compared to healthy controls, with NLRP3 activation correlating positively with disease severity (Algaba-Chueca et al., 2017)

Homocystinuria: An enzymatic defect