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Macpherson AJ, Slack E, Geuking MB, McCoy KD

La lac interviene sulla cascata di eventi che conducono alla morte cellulare: _formazione di radicali liberi

Neural regeneration following an injury can be potentially treated with Gly-Pro-Glu (GPE), the amino-terminal peptide of the insulin-like growth factor-1 (IGF-I)

For example, engineering EVs to overexpress stimulator of interferon genes (STING) directly activates antigen-presenting cells within the tumor and the cyclic GMP-AMP synthase (cGAS)-STING pathway, initiating anti-tumor immune responses and inducing the formation of tertiary lymphoid structures with cytotoxic functions [186]

Increased intrahepatic activation and proliferation of CD4 + T cells in NASH, along with increased IFN- and TNF- production, activation of the pro-inflammatory response in NASH [92, 93]