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USA 112 , 43344339 (2015)

The mechanism is well-documented: forced keratinocyte proliferation disrupts the cornified envelope, increasing transepidermal water loss by measurable amounts

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The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies

Since the lymphatic system drains out waste by-products and also has crucial immune system functions, its no surprise that lymphatics overburdened with harmful byproducts is less effective at fighting off infections