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It primarily exerted its effects by binding to the TrkB, which could regulate neuronal maturation, synapse formation, and synaptic plasticity [120]

10.1046/j.1365-313X.1997.12040875.x Plant J

Suzuki, Kohno H, Sugie S, Murkami A, Yano M, Ohigashi H, Tanaka T

These findings suggest MK-677 influences sleep regulation, but its long-term safety and real-world benefits still need more investigation before drawing firm conclusions