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AIM2 suppresses ferroptosis by promoting proteasomal degradation of FOXO3a, a transcriptional activator of ACSL4 a key enzyme that esterifies PUFAs into peroxidation-prone phospholipids essential for ferroptosis execution (259)

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Heath, P

Exclusion criteria : Case reports, letters to the editor, conference abstracts, and unpublished data with insufficient detail on study design, sample size, or mechanistic endpoints were excluded