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Outcomes were evaluated from CTE start to 3 months since last use, including hypertension (HTN), VTEs, myocardial infarction (MI), stroke, pregnancy, and pelvic inflammatory disease (PID), identified by ICD codes and chart validation

Song B, Wei F, Peng J, et al

First, there is no definitive cure

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Third, should population-level newborn genome sequences become available in the future, genome interpretation using the CBS variant effect map has potential value, even in the absence of elevated methionine or early childhood symptoms