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Analysis of the data indicates that short-term treatment with RM-493 increased resting energy expenditure significantly (by 6.4% vs placebo), thus suggesting RM-493 may be clinically effective for treating obesity

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Conclusion Adhering to lab best practices for bacteriostatic water handling and storage is fundamental to maintaining research integrity and ensuring reliable experimental outcomes

17 Moreover, other trials as the SUSTAIN-6 trial showed that semaglutide, another GLP-1RA also reduced the risk of MACE by 26% and non-fatal stroke by 39% in patients with T2DM