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Additional studies on silymarin and its possible impact on the health of the urinary tract, especially cystitis, will therefore be useful in the effort to establish the other uses of the substance apart from conditions affecting the liver

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Peripheral blood response to multiagent induction therapy Patients with persistent circulating leukemia cells at 7 to 10 days after the initiation of multiagent chemotherapy are at increased risk of relapse, compared with patients who have clearance of peripheral blasts within 1 week of therapy initiation.[149] Rate of clearance of peripheral blasts has been found to be of prognostic significance in both T-cell and B-lineage ALL.[149] Peripheral blood MRD before EOI (day 8, day 15) MRD measured in peripheral blood obtained 1 week after the initiation of multiagent induction chemotherapy has also been evaluated as an early response-to-therapy prognostic factor