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doi:10.3346/jkms.2015.30.9.1213 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( Source: Wieers, Michiel L A J et al

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Statements Author contributions JX: Writing original draft, Funding acquisition, Resources, Formal analysis, Software, Visualization, Methodology, Data curation, Investigation

A useful interpretation of the data: Semax appears most measurable when the brain is under a perturbation (stress, ischemia, fatigue, learning load) rather than as a constant baseline amplifier