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The most common cause of Vitamin B12 deficiency is a lack of intrinsic factor, a protein the stomach produces that is essential for B12 absorption

FSA is conducted for important metabolites such as ATP, NADPH, NO, succinate, and itaconate in normal (without turning off any pathways), glycolysis off and OXPHOS/TCA off condition

Ferroptosis is a recently described form of programmed cell death caused by uncontrolled iron dependent lipid peroxidation that distinguishes it from traditional modalities of regulated cell death including apoptosis, necrosis, and autophagy (Li et al., 2020a)

And like many solid tumors, prostate cancer also has proven stubbornly resistant to newer immunotherapies, which are intended to take the brakes off the immune systems T cells to get them fighting cancerous invaders