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Elevated activity in the sera of brain cancer patients of the same isoenzyme where high activity was found in cancer cells seems to be the result of its releasing from tumor cells

Regulation of Glutaminolysis Glutaminase (GLS) is the first and rate-limiting enzyme in the glutaminolysis pathway

A limitation of current research is that most studies focus on NSCLC, with limited investigations into other types of LC (156,157)

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