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In addition to traditional CIs, a study of a newly proposed artificial CIs shows great potential

The following primary antibodies was added: YAP1 antibody (1:1000, affinity, AF6328), SLC1A5 (1:2000, abcam, ab237704), GLS1 (1:2000, abcam, ab156876), histone H3 (1:2000, abcam, ab1791), GAPDH antibody (1:1000, abcam, ab9485), and the membrane was incubated at 4 C overnight

Although the mechanisms are not fully elucidated, it is clear that IgA interacts with both bacteria and food antigens within the lumen of the gut, and this is likely to be important for maintaining intestinal homeostasis that suppresses allergic inflammation (summarized in Fig