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A major one is any product labeled for research only. This is a way some sellers skirt the fact that their product isnt FDA-approved, and it basically means the drug or supplement isnt meant for human use or treatment

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Without this, you would start eating back the way you did before the diet and would regain the weight faster because your metabolism hasnt fully reset to the new higher calorie level

These overlapping limitations highlight an urgent need for further validation through large-scale, single-strain, long-term follow-up multicenter RCTs