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Fisetin inhibits the generation of inflammatory mediators in interleukin-1-induced human lung epithelial cells by suppressing the NF-B and ERK1/2 pathways

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A study on metabolically healthy men found that 12-week synbiotic intervention significantly reduced serum alanine aminotransferase levels, with a 20.70% reduction in the subgroup with elevated body fat percentage, and significant changes in gut microbiome composition occurred in this subgroup, suggesting synbiotics may exert hepatoprotective effects on specific populations by regulating gut flora