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Cancer history / active malignancy: compounds that promote angiogenesis and cell migration (BPC-157, TB-500) are generally treated as contraindicated where uncontrolled cell growth is a concern a standard caution across the recovery-peptide literature

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doi: 10.1210/jcem-29-1-20 12 SassinJFParkerDCMaceJWGotlinRWJohnsonLCRossmanLG

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Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

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