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In the UPS, proteins are selectively marked by ubiquitination, the covalent addition of ubiquitin (Ub) molecules to lysine residues, which signals and targets the protein for proteolytic degradation by the 26S proteasome

Low glutathione levels have been linked to oxidative stress which may play a role in conditions such as cardiovascular disease and inflammatory bowel disease

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As discussed above, characterized with great biocompatibility, non-toxic property and non-immunogenic feature 86,87 , liposome is a great delivery system for dietary polyphenols and exhibit excellent encapsulation properties such as good aqueous solubility and slow release ability to enhance the bioavailability of dietary polyphenols 88

doi:10.3390/jpm11111141