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1995 FDA approval milestone: The US FDA approval of liposomal doxorubicin (Doxil) in 1995 marked the first time a nanomedicine entered routine clinical practice, demonstrating that lipid-based carriers could meet regulatory, safety, and quality expectations [1]

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Five out of 16 patients showed an anion gap below the reference range of 816 mmol/L during simultaneous use or within 48 h after withdrawal of one of the drugs

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Decreased plasma concentrations of apolipoprotein M in sepsis and systemic inflammatory response syndromes