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You can experience positive changes in the first three months of treatment

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Growth-hormone-axis peptides such as tesamorelin and CJC-1295 are typically considered as one element of a broader, individualized plan rather than on their own

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These include: reduced cardiac output and exercise capacity (beta-1 effects on the heart) blunting of sympathetic fight or flight activity sleep related effects (see below) Based upon a meta-analysis involving over 35,000 participants, the overall incidence of fatigue in patients treated with beta blockers (including metoprolol) was 7.1% compared to 4.3% of placebo-treated patients (an absolute excess of ~2.8%)(Ko et al, 2002)