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Common side effects include: Nausea and vomiting Diarrhoea or constipation Reduced appetite (which is also a therapeutic effect) Injection site reactions (redness, bruising, or mild discomfort) These effects are typically mild to moderate and tend to resolve as the body adjusts to the medication

however, the exact mechanism of topiramate treatment of migraine deserves further investigation, as there is less experimental evidence of topiramate prophylactic treatment of migraine

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Blood-based biomarkers in Alzheimer's disease: advancing non-invasive diagnostics and prognostics