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Sci Adv (2019) 5(6):eaav7769

IKBKE regulates angiogenesis by modulating VEGF expression and secretion in glioblastoma

Poly(A) + RNA-selection Total RNA was extracted using TRIzol (Thermo Fisher, 15596018) according to the suppliers protocol

Although the brain only accounts for 2% of body weight (Mergenthaler et al., 2013) and mitochondrial density is higher in myocytes than in neuronal cells (Gandhi and Abramov, 2012), it is an organ with a high metabolic rate that can consume up to 20% of the total oxygen of the body (Moreira et al., 2009