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Description

These simulations reveal altered binding sites, structural changes, and disrupted interactions, shedding light on disease mechanisms

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In the absence of F

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Prostaglandin E2 (PGE2), the most important bioactive mediator secreted by neutrophils, accelerates blood flow and produces oedema and pain, and its synthesis is primarily related to AA, which is related to LDs (Kawahara et al., 2015)

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Inflammation is a defensive reaction of the body that arises after microbial invasion, exposure to antigens, or cellular and tissue injury

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The accumulation of lipid droplets, rich in polyunsaturated fatty acids (PUFAs), also creates vulnerability to ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation [18, 19]

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