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The evidence: where it's strongest, where it's weaker 1

While a substitution with the polar serine at position 13 retained wild-type dehydratase activity, presumably due to the alcohols ability to assume cysteines function in stabilizing deprotonated GS , the only other Pt GSTF8 variants to keep analbeit reducedflavan-3,3,4-triol ( 4 ) dehydration activity contained a glycine, alanine or asparagine mutation (Fig

and Faecalibacterium prausnitzii are the two most abundant butyrate producers, typically constituting 510% of the detectable fecal bacteria in healthy adults [13]