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In the P1 data-set (Table 1, pan- el A), the responses in group A were found to be signi cantly different from the pre-exposure data at every frequency ex- cept 9 kHz

60 capsules (60-day supply) and 120 capsules (120-day supply) at one capsule per day

79, Supplementary Table 1 and 2, and Supplementary Data 1) demonstrate that rearrangement of surrounding residues could allow BV to bind with Ab Pcob in certain conformations, where hydrophobic interactions with residues in the binding pocket (e.g., Leu252, Trp289, Leu294, Arg297, Val299 and Val303) contribute to retain BV in the correct orientation (Fig

doi: 10.1016/j.cell.2020.07.020 14