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Vitamins K, P and C are the primary fighters against breakability and permeability of the blood vessel walls

In a spontaneous lupus erythematosus mouse model, oridonin has been shown to diminish proteinuria and renal damage, while in vitro investigations have indicated that this compound reduces inflammatory cytokine production and the inflammatory cascade triggered by LPS following oridonin treatment (Tan et al., 2021)

Prolonged NSAID use similarly interferes with repair processes

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Shields A., Ly S., Wafae B., Chang Y.F., Manjaly P., Archila M., Heinrich C., Drake L., Mostaghimi A., Barbieri J.S