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Back to Journals Pharmacogenomics and Personalized Medicine Volume 9 CYP2D6 polymorphisms and their influence on risperidone treatment Authors Puangpetch A, Vanwong N, Nuntamool N, Hongkaew Y, Chamnanphon M , Sukasem C Received 5 July 2016 Accepted for publication 15 September 2016 Published 1 December 2016 Volume 2016:9 Pages 131147 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Martin Bluth Apichaya Puangpetch, 1 Natchaya Vanwong, 1 Nopphadol Nuntamool, 2 Yaowaluck Hongkaew, 1 Monpat Chamnanphon, 1 Chonlaphat Sukasem 1 1 Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, 2 Molecular Medicine, Faculty of Science, Mahidol University, Bangkok, Thailand Abstract: Cytochrome P450 enzyme especially CYP2D6 plays a major role in biotransformation

As shown in Table 1, GLCA, GHDCA, and GDCA were all considerably higher in the LT2 group than in the Model group

The combination of 2 potent NUCs might have additive or synergistic antiviral activity, which may result in faster or more profound viral suppression