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An alternative to increasing the bioavailability of CSA-13 after intravenous administration may be the use of ceragenin-based nanosystems

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Bispecific nanobody activity measured by macrophage phagocytosis Previous studies have demonstrated that PD-L1 antibodies can significantly enhance the proliferation and activation of macrophages in vivo, leading to a proinflammatory phenotype 29,30