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Patients undergoing lower gastrointestinal investigations or endoscopy for rectal cancer diagnosis were recruited between October 2020 and January 2022 from St

Asthana et al., 2021), not only protected the cultured DRG neurons from mitochondrial dysfunctions after vincristine treatment (Chine et al., 2019b), but also prevented the mitochondrial swelling in both myelinated and unmyelinated axonal fibers of sciatic nerves, and apoptosis in the DRG neurons (Chine et al., 2019a,b)

Under oxidative stress, Nrf2 translocates to the nucleus and binds to the antioxidant response element (ARE), promoting the expression of enzymes involved in the synthesis of SOD, CAT, and glutathione 36