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Modifications in monoamine neurotransmitter function, altered stress-responsive mechanisms, and brain inflammation are all regulated by genetics

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Moreover, to bridge the gap between bench and bedside, we employ an SD rat model of AD, providing a dynamic in vivo platform to unravel the nuanced effects of m6A-modifying genes on AD progression, cognitive function, and macrophage polarization within the intricate milieu of the disease microenvironment