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Disclosures: Siham Abdelgani: Nothing to Disclose 883 HBS ISOFORMS AS INNOVATIVE BIOMARKERS IN PREDICTING VIROLOGICAL RESPONSE TO BULEVIRTIDE MONOTHERAPY IN PATIENTS WITH CHRONIC HEPATITIS DELTA Stefano D'Anna 1 Romina Salpini 1 Elisabetta Degasperi 2 Leonardo Duca 3 Maria Paola Anolli 4 Lorenzo Piermatteo 1 Dana Sambarino 4 Marta Borghi 4 Francesca Ceccherini Silberstein 3 Floriana Facchetti 4 Riccardo Perbellini 4 valentina svicher 1 Pietro Lampertico 5 , 1 Department of Biology, University of Rome Tor Vergata, Rome, Italy, 2 Division of Gastroenterology Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy, 3 Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy, 4 Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy, 5 University of Milan Background: HDV exploits HBV surface protein (HBsAg) for its morphogenesis and entry into hepatocytes

The usage of the above drugs and the intervention course are detailed in Table 1

For HFA inhalers, adults typically use 1 to 2 puffs every 4 to 6 hours as needed

8 weeks 56 syringes 1 syringe per day