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Animals and housing Following laboratory animal welfare (3Rs: Replacement, Reduction, and Refinement) best practice [31], we acquired 13 adult female mice (C57BL/6 background) from another lab which were excess to experimental requirements, experimentally nave, and slated for euthanasia

This unique property imparts to the receptor the capacity to sense the membrane potential and open only when the neuron is depolarized

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Oxidative stress contributes to liver damage in a murine model of alpha-1 antitrypsin deficiency