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doi: 10.1155/2023/4839124 45 RdeiDKszNRafaiTBogdanovABurinKCsorbaAet al

For example, under fasting conditions, AMPK and PPAR synergistically activate autophagy through transcriptional and epigenetic reprogramming, whereas in inflammatory states, NF-B and IRF8 may suppress or redirect autophagic flux toward immune-specific outcomes

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This contradicts the antioxidant properties of curcumin, the potential reasons for which are discussed in the present review

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