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AhR controls the expression of the SOD1 gene [85] and plays a role in neuronal signaling [86]

There are hundreds of compounds in coffee, namely caffeine, diterpenes, potassium, niacin,magnesium, antioxidants, chlorogenic acids and tocopherols [60]

However, a crosssectional analysis of the ADNI cohort yielded contrasting results, showing that serum ALT levels in AD patients were significantly lower compared to cognitively normal controls