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Calcium homeostasis is maintained through SERCA2a activation to enhance calcium reuptake and restore normal flux, while inhibiting Ca 2+ -dependent calcineurin/calpain/CaMKII activity to prevent calcium overload-induced remodeling (Hedayati et al., 2023)

A medical consultation is always required, and we openly decline treatment when it is not in the patient's interest

Remission was maintained for more than a year in 85% of cases, with no relevant differences between concentrations

The resulting smaller and more mobile mitochondria can redistribute to the oocytes cortical region, meeting the energy and structural remodeling needs during maturation [54, 89]