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Eur J Haematol 60:267268

It also manages oxidative stress, particularly in dopaminergic neurons, by activating the Nrf2-antioxidant response elements (ARE) pathway and increasing the expression of antioxidant enzymes

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Histological evidence has shown that the activated T cells cross the BBB, invade the CNS, and congregate around small venules to trigger localized inflammation (Kuhlmann et al., 2017)