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The PVN receives major inputs from the amygdala, which plays a key role in the management of emotional stimuli (253, 274), and from the PBN in the brainstem, a hub nucleus for the detection of inflammatory stimuli (252)

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, mitochondrial dysfunction