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Bioinformatic studies have shown that genes associated with necroptosis are altered in the brains of PD patients compared to control subjects, suggesting an increased susceptibility to necrotic cell death in these patients (Lei et al., 2023)

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Increases in blood vessel constriction by COX-2 inhibition can also lead to the hypertension and renal failure seen in some studies of non-selective and COX-2 selective NSAIDs (Conaghan 2012)

Glossitis: A sore, red, or uncharacteristically smooth tongue

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