pentose phosphate pathway and glutathione - an overview Pentose phosphate pathway - Wikipedia

Figure 4 Figure 5 To test whether the reduction kinetics of roGFP2-iL is affected by GRX, roGFP2-iL was fused to the C-terminus of Hs GRX1 and the catalytic efficiency for the reduction of the resulting fusion protein by GSH was compared to free roGFP2-iL in in vitro experiments (Figure 6)

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However, this increase in the life span poses critical issues associated with the aging phenotypes, among which early-onset AD neuropathology and dementia represent the most disabling features with social and economic impacts