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Among these, histone acetylation, catalyzed by histone acetyltransferases (HATs) and reversed by histone deacetylases (HDACs) [127], has been particularly associated with hyperglycemia-induced endothelial dysfunction and inflammation [128]

In addition, the same study has reported the use of mouse model for breast cancer to confirm that inhibition of p38 MAPK conjoins with cisplatin therapy to decrease tumor size and malignancy [82]

J Hematol Oncol 13(1):156 Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S et al (2022a) Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway

Sci Rep 9(1):12646 Lee J, Fernandez K, Cunningham LL (2024) Hear and now: ongoing clinical trials to prevent drug-induced hearing loss

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