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This phenomenon is a hallmark observed in both human uveitis samples, including aqueous humor and peripheral blood mononuclear cell (PBMC) profiling, as well as in experimental autoimmune uveitis ( Importantly, Mucosal homeostasis critically depends on the coordinated activity of Th17 and Treg cells

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Specifically, the ceramide level is decreased in serine-depleted cells (3 in Fig

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