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Arsenic binding to ArsD As(III) metallochaperone Arsenic being the most common toxic element in the environment has resulted in the evolution of arsenic detoxifying mechanisms in nearly all organisms

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Immunoprecipitation studies revealed an increased association of FUS with XRCC1, LigIII, and PARP-1, but not with other base excision repair (BER) proteins in ALS patient-derived iPSC lines carrying FUS mutations (R521H and P525L)