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Many variants of G6PD, mostly produced from missense mutations, have been described with wide-ranging levels of enzyme activity and associated clinical symptoms

Investigating on nucleophiles, diverse aromatic rings were cross-linked with amines, mercaptans, and electron-rich aromatics modularly, affording aza-disulfides, trisulfides, and diaryl disulfides, respectively

(d) promoting antioxidant molecules and the expression of related genes involved in mitochondrial energy biogenesis, mainly through AMPK/SIRT1/Nrf2, ERK/p38 Mitogen-activated protein kinase (MAPK), and PTEN/Akt signaling pathways

Human evidence remains limited and primarily cosmetic

10.1016/j.celrep.2021.110166 169 WangM