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Each of the 430 compounds from a SelleckChem Kinase Inhibitor Library (subset of library #L1200) were combined at 100 M in wells of a polypropylene 96-well Tube Plates (Agilent) with TcPINK1 D337N at 0.5 mg/mL (10 M) and SYPRO Orange Protein Gel Stain 5000X (Thermo Fisher Scientific) at 6X in a 300 mM NaCl, 20 mM TrisHCl pH 8, 5 mM DTT, 5% DMSO buffer

This is one of the few GLP-1 formulations that genuinely does not need a refrigerator, making it the most travel-friendly option

Mol Cell Endocrinol 2015;402:43-50.ArticlePubMed 99

However, the most clinically relevant role of CYP2E1 is associated with ALC and APAP metabolism, especially at their higher doses