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However, there remains a significant gap in our understanding of genetic risk factors in other admixed populations, despite the increasing incidence of POAG 75,76 in these diverse communities

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3-month cycle structure: Clinical practice follows a loading phase, a maintenance phase, and a rest period before repeating

Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD