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It starts making less of what the body needs to recover from damage or stress

8.9 Volunteer Studies In experiments by Weger (1968) on seven volunteers, an intravenous dose of N,N- dimethyl- p- aminophenol (3.25 mg/kg) resulted in a 15% methaemoglobin concentration within 1 min

Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism